It consists of Oxandrolone which has both anabolic and androgenic effects. It is developed to treat anemias such as aplastic anemias in the sixties. It later became popular among bodybuilders due to its powerful anabolic effects. It is also famous for being effective in massive gain. There have also been links between oxymetholone treatment and the development of leukemia. Oxymetholone is considered to be a derivative of dihydrotestosterone (DHT), it has a reputation for being the strongest oral AS available. It is highly anabolic and androgenic, therefore it is very toxic to the liver. There have been many reports of acne and hair loss (due to its dihydrotestosterone characteristics), in addition to its strong association with liver damage and gynecomastia. There have also been reports of headaches and stomachaches. There is substantial evidence of size and weight loss, which has been attributed to the drug being too hard on the body. Very few women are able to tolerate oxymetholone due to its dominant androgenic effects such as virilization. Due to its side effects, it is recommended to keep the use below six weeks. On top of this it could be a poor choice for those who are naturally prone to high blood pressure.